A member asked:

I have anaphylaxis from benadryl (diphenhydramine) (documented by ed mds), is chlor trimeton ok to take instead?

5 doctors weighed in across 2 answers
Dr. Melissa Gowans answered

Specializes in Pediatrics

No guarantee: Chlortimeton is a different chemical compared to benadryl (diphenhydramine) (Alkylamine vs Ethanolamine derivatives) so in theory it should be ok.Actual anaphylaxis reaction to antihistamines is not only rare, but every case report, there have been other drugs involved (co-ingested). Consider specific allergy testing because anaphylaxis is life-threatening and if it wasn't the benadryl (diphenhydramine) you need to know absolutely.

Answered 10/17/2014

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Dr. John Chiu answered

The dye or gelatin?: It is unusual to become allergic to Benadryl (diphenhydramine) and thus I would consider the excipient present in Benadryl (diphenhydramine) or even the gelatin capsule to be better explanations. Consult an allergist to help you sort this out.

Answered 10/17/2014

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