HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

What is the best antihistamine for adjunct therapy to treat anaphylaxis (of course after epi... injection vs pills ex: atarax or benadryl (diphenhydramine)?

A doctor has provided 1 answer
Dr. Kristin Sokol answered

Specializes in Allergy and Immunology

Benadryl (diphenhydramine): Benadryl (diphenhydramine) is fast acting and is a good adjunct to epinephrine. However for the days following a severe allergic reaction, Zyrtec is great as it lasts a longer amount of time than Benadryl (diphenhydramine) and doesn't make you as sleepy. Atarax is fine but is a prescription medication and not indicated for acute allergic reaction

Dr Hegab and another doctor agreed

Answered 8/17/2016

1.4k views

Thank

Related Questions

A member asked:

I'm currently taking 275 of Benadryl (diphenhydramine) all day and singular,pepsid and Zyrtec along with prednisone. Have suffered with anaphylactic shock. Zofran ok ?

A doctor has provided 1 answer

A member asked:

Is it possible for someone to have anaphylactic shock from the active ingredient in benadryl (diphenhydramine)?

A doctor has provided 1 answer

A member asked:

30 weeks pregnant. Miserable itching rash that has spread all over body and face. Has tried benadryl, (diphenhydramine) atarax and multiple creams unsuccessfully?

5 doctors weighed in across 2 answers

A member asked:

Intense body itching x3 days, no rash. No changes in lotion, soap, conditioner, dryer sheets, etc. Benadryl (diphenhydramine) lasts 2-3 hrs, atarax lasts 4. Ideas!?

A doctor has provided 1 answer

A member asked:

Can you take Benadryl (diphenhydramine) & atarax together for itching, when taking percocet?

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

For adjunct therapy for anaphylaxis during prehospital treatment (not in ambulance)Would you prescribe your patient benadryl (diphenhydramine) pills or injection?
To treat non anaphylactic allergic reactions faster (hives and itchiness) would it be better to go with Benadryl (diphenhydramine) IM or Atarax IM?
Can Benadryl (diphenhydramine) be used to treat anaphylaxis?
Anaphylaxis to med yesterday, used epi/ER. Feel better, swelling/rash/fast heartbt etc. are gone except mild itching. Should I use benadryl (diphenhydramine)? Or?
I have anaphylaxis from Benadryl (diphenhydramine) (documented by ED mds), is chlor trimeton ok to take instead?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.