A member asked:

What is the best antihistamine for adjunct therapy to treat anaphylaxis (of course after epi... injection vs pills ex: atarax or benadryl (diphenhydramine)?

A doctor has provided 1 answer
Dr. Kristin Sokol answered

Specializes in Allergy and Immunology

Benadryl (diphenhydramine): Benadryl (diphenhydramine) is fast acting and is a good adjunct to epinephrine. However for the days following a severe allergic reaction, Zyrtec is great as it lasts a longer amount of time than Benadryl (diphenhydramine) and doesn't make you as sleepy. Atarax is fine but is a prescription medication and not indicated for acute allergic reaction

Answered 8/17/2016

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