A member asked:

On isotretinoin for almost a year. acne flared up as i was weaned off it, as well as severe mood drop. is there an underlying hormonal issue?

A doctor has provided 1 answer

Isotetinoin: Acctane is a a dangerous drug with potentially serious psychologic and psychiatric side effects which were reviewed with you in detail at the time of the initial treatment (17 page consent). You will need to be closely monitored as you are weaned off and may benefit from consultation with a mental health professional.

Answered 10/12/2014

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