A member asked:

Im taking cymbalta (duloxetine) 30mg and zoloft 50mg i fell very good with that mix is that ok?

4 doctors weighed in across 4 answers
Dr. Richard Zimon answered

Specializes in Internal Medicine

Sounds great!: You are at minimal doses of both drugs. Sounds fantastic! Onward and Upward! Hope this helps Dr Z

Answered 4/10/2015

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Dr. Carlos Barrios answered

Specializes in Child Psychiatry

Not ok.: You are taking two serotonin increasing medications and putting yourself at risk for seratonin syndrome & can overactivate cardiovascular and neurlogic autonomic system e.g. mild tremors al the way to cardiac arrhythmeas and seizures possible; can be life threatening. Instead pick one of the two and maximize it- preferably the ssri. Cymbalta (duloxetine) ups norepi which fuels anxiety. C ur doc asap plz.

Answered 4/10/2015

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Dr. Stephen Southard answered

Specializes in Internal Medicine

As long as your: doctor has warned you about the rare possible effects of high serotonin levels, due to similar effects of the medications on your body's serotonin levels it isn't unreasonable. Watch for agitation, racing heart rate, muscle twitching, diarrhea, sweating. Remember, everyone is different and responds to different combinations of medications.

Answered 4/10/2015

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Dr. David Lipkin answered

Specializes in Internal Medicine

Use with caution: Risperidal, Cymbalta (duloxetine) and Zoloft can interact with each other and on occasion can cause a form of toxicity called the Serotonin Syndrome. These medications elevate serotonin, a neurotransmitter, that enables one neuron(nerve cell) to communicate with another. When mixed together they can cause the serotonin level to go too high. See http://bit.ly/1CvRfjC Do not stop medication on your own.

Answered 4/10/2015

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Related Questions

A member asked:

Would a taper from 60 mg of cymbalta (duloxetine) to Zoloft be difficult?

3 doctors weighed in across 2 answers