A member asked:

I'm tapering off zoloft and switching to cymbalta (duloxetine), (duloxetine) will i lose weight with cymbalta (duloxetine).. with out the zoloft? (at the moment i am taking both)

2 doctors weighed in across 2 answers
Dr. Paul Grin answered

Specializes in Pain Management

Loss of appetite: Both medications have as a side effect- loss of appetite. However, with Cymbalta (duloxetine) is an individual response, you can gain or loose weight. At the same time Cymbalta (duloxetine) is a good antidepressant (snri) and chronic pain relief medication.

Answered 6/24/2014

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It would be best if your medication is managed by a Psychiatrist. If you are not confident with your doctor please see another for a second opinion.

Answered 7/27/2022

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