A member asked:

Is muscle fasciculation size/intensity a clue in considering bfs vs als onset? i've had intense, large fasciculations in feet and calfs for a week.

3 doctors weighed in across 3 answers

Not helpful: You may possess fasciculations in your legs, but that alone does not confirm ALS, as these muscular reactions may be seen with fatigue, muscular irritability, thyroid or medication reactions, and even with a variety of peripheral nerve issues. Can best be sorted out by a neurologist, and if questions remain, an EMG study may be very useful.

Answered 9/13/2014

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No: Benign fasciculation syndrome (BFS) is a neurological diagnosis of exclusion. The nature of fasciculations in BFS and ALS may not be differentiated clinically. However, see a neurologist if you're concerned. Electrodiagnostic differences have been reported in small studies. Common causes of BFS include anxiety, medications, toxicity. http://www.nlm.nih.gov/medlineplus/ency/article/003296.htm

Answered 9/13/2014

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Not so simple: Fasiculations can be a sign of muscle denervation or simply muscular fatigue. Don't jump to unwarranted conclusions. See if they last and if they do see a good neurologist

Answered 9/29/2016

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