A 37-year-old female asked:
How n why is it that m spike is below 1 but plasma cells are 15 percent in the bone marrow pls kindly explain?
1 doctor answer • 1 doctor weighed in
A Verified Doctoranswered
Family Medicine 34 years experience
Immunohistology: Normal plasma cells in your bone marrow would not cause a high M spike. Rarely, abnormal plasma cells do not cause an M-spike.
Causes of reactive bone marrow plasmacytosis include infection, malignancy, inflammation, Castleman’s disease, anemia, diabetes mellitus, cirrhosis. In most cases the plasma cell infiltrate is less than 20%, The cytoplasmic light chain ratio differentiates MUGUS
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3.7k viewsAnswered >2 years ago
Last updated Sep 29, 2016
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