HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

10mg (low dose) omeprazole for long term gerd treatment? will this cause magnesium or b12 deficiency?

A doctor has provided 1 answer
Dr. Paul Grin answered

Specializes in Pain Management

It is possible: Taking Omeprazole for a long time could lead to mineral and Vitamin deficiencies due to resulting lack of acid in the stomach. Many natural supplements and home remedies are available, but discuss them with your doctor first. Take care.

Dr Mahnensmith and another doctor agreed

Answered 9/3/2014

3.7k views

Thank

Related Questions

A member asked:

I am a 51 year old woman. I have GERD, have used Omeprazole daily for over 20 years. The medication no longer seems to be helping as I have acid reflux constantly. I also have IBS. Is the PPI causing low stomach acid making me worse? Should I stop?

A doctor has provided 1 answer

A member asked:

Is it smart to take a calcium, magnesium and B12 supplement in the morning, and then take omeprazole (prilosec) in the afternoon after dinner?

A doctor has provided 1 answer

A member asked:

Have gastritis and on omeprazole for 6 mo now. Worried about vit b12, calcium, and iron deficiency. What should I do to avoid a deficiency?

A doctor has provided 1 answer

A member asked:

I'ma long term user of omeprazole & also on domperidone. I get fatigued a lot cud this b vitamin B12 deficiency & if so when would b best to supplement?

3 doctors weighed in across 2 answers

A member asked:

January 2019- February 2021 my Vitamin B12 dropped from 617 to 158. Then from February 2021-March 2021 it dropped to 114. Is this pattern more concerning than a typical deficiency? I take RX Pepcid 2x daily for GERD. Not sure if that plays a role?

A doctor has provided 1 answer

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

Is there anything as effective as omeprazole for GERD that doesn't cause B12 deficiency? It has become severe.
Will magnesium supplements as mag oxide 500 mg be absorbed if I have GERD or gut infections. On omeprazole too. Reflux , bone pain, anxiety, nervy!
I have this irritating cough from GERD, I know Omeprazole is one of proton inhibitors used in the treatment. What's the appropriate dosage to treat it. I used to rush my food which I'm gradually taking care of, but no other issue except coughing?
My doctor told me to take omeprazole 20mg, once a day for gerd. my roomate bought omeprazole magnesium instead. Are these interchangeable?
Can Omeprazole cause long term problems. If so what can I do to help eg B12 or magnesium supplement?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.