A member asked:

I'ma long term user of omeprazole & also on domperidone. i get fatigued a lot cud this b vitamin b12 deficiency & if so when would b best to supplement?

3 doctors weighed in across 2 answers

Many causes: There's so many causes for fatigue. If this is really troubling you get a check up. B12 deficiency, among other causes are really easy to check. It's unlikely B12 def it's the cause but again anything possible. Stress, other causes of anemia and thyroid are among some things to look into.

Answered 6/24/2014

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See details: Stop the omeprazole. A recent study: proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency jameson r. Lam, mph1; jennifer l. Schneider, mph1; wei zhao, mph1; douglas a. Corley, md, phd1 showed that Omeprazole and other proton pump inhibitors can cause B12 deficiency.

Answered 9/28/2016

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