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A member asked:

What does muscle weekness on thumb and index finger of hand feel like in als ?

A doctor has provided 1 answer

ALS symptoms: People with ALS have a painless, progressive weakness. It may start in the muscle between the thumb and index finger (the first dorsal interosseous muscle or FDIH). Normally, their symptoms occur throughout the body, although they can be worse in both arms, or both legs, or in the face, etc.

Dr Altman agreed

Answered 1/28/2020

3.8k views

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38 yo,healthy woman.The base of my thumb twitches randomly,causing thumb to move. For past 5 months,have noticed in same hand index finger sometimes,too.NO weakness or anything.IF ALS,would something else be happening by now?I do work at computer.
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