Throbbing in knee, calf cramps and uncomfortable feelin in foot and ankle. it feels like my veins are too full? what could this be? neg ddimer and us

The good news is: You were examined for the most dangerous thing a clot. Now,follow up with an orthopedist to figure out if there is any structural issues with the knee or calf.

Inflamed veins: Pain in calfs with a heavy feeling can be caused by venous congestion or inflammation. Another possibility is a cellulitis if your legs are warm or hot to touch. You could also have superficial or deep phlebitis affecting your legs. I would go to my internist then see a vascular specialist. Try to apply warm compresses to see if it gets better. Good luck.

Check your nerves: I suggest checking your nerves with NCV test of the lower extremity.