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A 32-year-old male asked:

is it safe to take arthrotec (diclofenac and misoprostol) and 650mg acetaminophen at the same time or does it need to be spaced out a certain amount of time? thanks!

2 doctor answers2 doctors weighed in
Dr. Andrea Rodgers
Emergency Medicine 28 years experience
You can but...: Arthrotec (diclofenac and misoprostol) is a non-steroidal anti-inflammatory medication. It doesn't interact with acetaminophen, but I think you might get better pain control if you spaced them out. If you take your Arthrotec (diclofenac and misoprostol) three times a day wait four hours after your dose then take the acetaminophen. Give it a try and see if you have better pain control.
Dr. Donald Collins
Dr. Donald Collinsanswered
Family Medicine 41 years experience
Yes: You can take acetaminophen with arthrotec (diclofenac and misoprostol). Be sure you do not take more than 4000 mg acetaminophen in a day. Good luck!

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Last updated Apr 24, 2015

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