A member asked:

Can one have spondilytis without hla-b27? have been tested neg. rheumy thinks it is anyway. women45, healthy/active. no inflam on blood test yet edema

5 doctors weighed in across 2 answers

Yes: All of the diseases which cause inflammatory back pain and or spondyloarthropathies can be HLA B27 negative. Sounds like you have a goodup to date rheumatologist

Answered 8/1/2014

3.8k views

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Dr. Dustin Colegrove answered

Specializes in Internal Medicine

Yes: you can have ankylosing spondylitis without being positive for HLA B27

Answered 8/2/2014

3.8k views

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