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A 22-year-old female asked:

Is it possible to have a lupus flare with normal labs (cbc, comp met, c4, c3, ua, sed rate and crp)? i have a lot of joint swelling/pain and mouthsore

1 doctor answer3 doctors weighed in
Dr. Martin Raff
Infectious Disease 58 years experience
SLE: What you describe is unusual but nothing is impossible. The non-specific markers of inflammation (ESR, CRP) being negative is quite remarkable. Think you might want to contact your rheumatologist and go over this with them. Good luck.
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