A 22-year-old female asked:
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is it possible to have a lupus flare with normal labs (cbc, comp met, c4, c3, ua, sed rate and crp)? i have a lot of joint swelling/pain and mouthsore

2 doctor answers
Dr. Ronald Krauser
51 years experience Rheumatology
Yes: Yes it is possible.
Answered on Jul 28, 2014
Dr. Martin Raff
55 years experience Infectious Disease
SLE: What you describe is unusual but nothing is impossible. The non-specific markers of inflammation (ESR, CRP) being negative is quite remarkable. Think you might want to contact your rheumatologist and go over this with them. Good luck.
Answered on Mar 27, 2018

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See details: I would doubt lupus. The rash is more likely to be rosacea.. Epistaxis is not a feature of lupus especially if the CBC is normal. Look for other cause ... Read More

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