A member asked:

I was prescribed viibryd (vilazodone hydrochloride) 10mg daily and mirtazapine 7.5mg at bedtime daily. haven't started mirtazapine yet. i'm worried about serotonin syndrome.

2 doctors weighed in across 2 answers
Dr. Anthony Vita answered

Specializes in Psychiatry

Exact risk unknown: Vilazodone (Viibryd) is a newer medication that acts as an SSRI (serotonin reuptake inhibitor) and also has additional effects at a serotonin receptor. Mirtazapine increases serotonin and norepinephrine and has antihistamine properties and thus it often helps insomnia. The exact risk of serotonin syndrome with this combination is unknown, but it is not zero. Talk to your MD about options.

Answered 7/16/2014

3.9k views

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Dr. Alan Ali answered

Specializes in Psychiatry

Viibryd/Remeron: No worries at these low doses.

Answered 4/3/2015

3k views

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