How is vincristine used?

Chemotherapy: Variety of cancers, leukemias...Acts by affecting microtubules....

Vincristine is used: To treat a wide array of cancers in children and adults, including hematologic malignancies, central nervous system cancers and a host of solid tumors as well. It impairs the functioning of microtubule assemblies, such as the mitotic spindle, and therefore blocks cell division. Interesting tidbit...It was originally isolated from periwinkle (aka, vinca), hence its designation as a vinca alkaloid.

Chemo agent: Vincristine is a chemotherapeutic agent also known as Oncovin (vincristine). It is primarily employed in the treatment of lymphomas and Hodgkins disease, usually in combination with other drugs such as in CHOPP. Side effects include nausea, hair loss and neurologic loss of balance. It works partly by binding to the tubulin protein, stopping the cell from separating its chromosomes during metaphase