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A 43-year-old member asked:

clozapine is making friend act weird, is that a normal side effect?

2 doctor answers2 doctors weighed in
Dr. Ed Friedlander
Pathology 44 years experience
No: Speak to your friend and feel free to call his/her physician. A true friend is ready to speak up when something like this happens.
Dr. Heidi Fowler
Psychiatry 25 years experience
Not normal: Per Drugs.COM agitation or confusion can occur in 1 to 10% of people taking Clozapine. People who are taking Clozapine may be taking if for conditions like Schizophrenia, Schizoaffective Disorder or Bipolar Disorder. So your friend may be showing symptoms of a mental health condition or this could be adverse effect. Your friend should tell his/her psychiatrist.

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Similar questions

A 47-year-old member asked:

Anyone out there taking clozapine (or clozaril)? What is it?

2 doctor answers2 doctors weighed in
Dr. Chris Esguerra
Psychiatry 16 years experience
Strong antipsychotic: Clozaril/clozapine is an effective antipsychotic medication with many cautions and potential side effects requiring regular blood tests. It can be effective for severe or difficult to treat schizophrenia. Given the potential side effects and requirement of blood tests, many doctors try other, safer medications or combinations first.
A 34-year-old member asked:

Clozaril (clozapine) long term side effect?

2 doctor answers2 doctors weighed in
Dr. Joseph Woods
Pathology 28 years experience
Has many.: There appear to be many side effects with this antipsychotic medication. Common ones are extreme constipation, bed-wetting, night-time drooling, muscle stiffness, sedation, tremors, orthostasis, hyperglycemia, and weight gain. Others are agranulocytosis, CNS depression, leukopenia, neutropenia, seizure disorder, bone marrow suppression, dementia, hypotension, and myocarditis.
A 39-year-old member asked:

What is the medicine clozapine used for?

2 doctor answers3 doctors weighed in
Dr. Shalabh Bansal
Pediatrics 13 years experience
Clozapone: It is an atypical antipsychotic used in treatment of schizophrenia and off label usage including bipolar disorder.
Canton, OH
A 39-year-old female asked:

Can clozaril (clozapine) be used to treat severe insmnia?

4 doctor answers8 doctors weighed in
Dr. Carlos Satulovsky
Psychiatry 28 years experience
Overdo: In theory; but it s not indicated (off label) and hard to justify the risks involved (agranulocytosis, seizures, death) not to mention the monitoring required. It should not be an alternative.
Dr. Tariq Halim
Dr. Tariq Halim commented
Psychiatry 14 years experience
It is not indicated for treatment of insomnia. Clozaril should only be used for treatment-resistant schizophrenia (after failing 2 other treatments) due to the potential for life-threatening side effects.
Sep 16, 2013
South Africa
A 22-year-old male asked:

How long after being on clozapine does its sedating effects go away? I'm supposed to take it in the morning too but it's way too sedating so i don't.

1 doctor answer1 doctor weighed in
Dr. Heidi Fowler
Psychiatry 25 years experience
Sedation: Please see article “Sedation side effect of clozapine”. REF: https://smiadviser.org/knowledge_post/sedation-side-effect-with-clozapine. Sedation can increase with each dose increase. It does tend to decrease over time (but I can't say how long that takes). People often take it at night if overly sedated or drink something like coffee if too sedated in morning.

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Last updated Jan 10, 2021

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