Topical retinoid: Prescription strength topically applied retinoids, such as tazarotene or tretinoin, can help thicken and strengthen the dermis after months of use. For quicker and more dramatic cosmetic results, "fillers" such as Restylane (dermal fillers) can be injected into localized areas to help soften any wrinkles caused by volume depletion.
Answered 8/19/2016
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