A member asked:

Is combining ambien (zolpidem) cr with 50mg of trazadone safe? ambien (zolpidem) isn't working anymore and i have trazadone was wondering if i can take if ambien (zolpidem) fails?

A doctor has provided 1 answer
Dr. Amanda Itzkoff answered

Specializes in Psychiatry

Trazadone or ambien (zolpidem)?: Before you make any changes to your medication regimen, you should discuss thoroughly with your provider. Now sounds like a good time to leave your doc a message about how Ambien (zolpidem) has become ineffective (which is one of the many drawbacks of habit forming meds). While technically there is no interaction b/w Ambien (zolpidem) & trazodone, if Ambien (zolpidem) is no longer working, perhaps discuss stopping that one?

Answered 5/9/2016

4.1k views

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