HealthTap Online Primary Care Doctors Accepting New Patients
Book a video visit
HealthTap
Telehealth
A member asked:

Can i take 100mg trazadone with 10mg ambien (zolpidem)?

A doctor has provided 1 answer

Probably ok: Check with your prescribing doctor before mixing medicines. There's no special danger in using these together — i sometimes prescribe both, as Ambien (zolpidem) helps mainly with falling asleep and trazodone with staying asleep. But since they are both sleeping pills, the effect is additive and there's a risk of over-sedation.

Dr Pappas and another doctor agreed

Answered 3/16/2015

5.1k views

Thank

Related Questions

A member asked:

Is it safe to take ambien (zolpidem) and trazodone? Ambien (zolpidem) helps to fall asleep but the trazodone helps to stay asleep.

A doctor has provided 1 answer

A member asked:

Is it dangerous to take 2 mg of klonopin, 10 mg of ambien (zolpidem) and 50 mg of trazodone all within a half hour in order to sleep? I'm a 140 lb woman.

7 doctors weighed in across 3 answers

A member asked:

I want to stop taking so many meds. Have severe insomnia and some anxiety. I take 150 trazadone, 10 ambien, (zolpidem) and .5 lorazepam nightly. How do I do this?

A doctor has provided 1 answer

A member asked:

Dr stopped my Ambien (zolpidem) for insomnia. Tried Trazadone 25 mg.for 1 month, lethargy next day unbearable. Now I'm to take 10 mg melatonin, as 5mg did nothing. Seems like huge dose. Ambien (zolpidem) worked perfectly. ?

5 doctors weighed in across 2 answers

A member asked:

Can I take Seroquel indefinitely for chronic primary insomnia? 12.5 mg has stopped working after 18 days. Should I increase it? Ambien (zolpidem) no longer works for me. Neither does Trazodone.

6 doctors weighed in across 3 answers

Sponsored Content
HealthTap Medical Group does not endorse products or services. Sponsored content revenues support our mission to make health information free and accessible to all.Learn more

People also searched for:

Can I mix 5mg Ambien (zolpidem) and 50mg trazodone? My Dr added the Ambien (zolpidem) but didn't say how exactly to take the two together
Is combining Ambien (zolpidem) cr with 50mg of trazadone safe? Ambien (zolpidem) isn't working anymore and I have trazadone was wondering if I can take if Ambien (zolpidem) fails?
Can I take my trazodone 300mg with my newly prescribed ambien (zolpidem) for my severe insomnia?
I take trazodone1x50mg at night and low-dose Ambien (zolpidem) taken as needed. Trazodone doesn't seem to get me to sleep; may i add half an ambien (zolpidem)?
Take trazadone and Ambien (zolpidem) to sleep, why do I feel so weird the next day and don't remember sleeping? Could i not be?

Telemedicine

Primary Care
Manage Your Conditions
Women's Health
Children's Health
Men's Health
Senior Health
Wellness, Prevention & Lifestyle
Sexual Health
Mental & Behavioral Health
Travel Medicine
Urgent Care
Ask your question
Didn't find what you're looking for?

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.

Ask your question

More of what we treat

Allergies
Antibiotics
Asthma
High Blood Pressure
Prescriptions
Type 2 Diabetes
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HealthTap
HIPAA logo
HIPAASecure
Soc 2 Type 2 logo
SOC 2 Type 2Certified
JCAHO Accredited
JCAHOAccredited
Member App

Download HealthTap

Video visit and message your doctor

Member App QR Code
Play Store Member LinkApp Store Member Link

Questions?

+1 (888) 828-0841support@healthtap.com
LinkedInTwitter
HomeTermsPrivacyCookiesDMCAHealth TopicsDoctors DirectoryDoctor Q&A by Specialty
Copyright 2026 HealthTap, Inc.