What can i do to increase chance of a successful pregnancy with pai and mthfr ?

Consult: I'm not familiar with the acronym PAI so you might want to rephrase your question describing that condition. I'm assuming it might have something to do with platelet problems. MTHFR used to indicate the need for Aspirin daily during conception and pregnancy. But that recommendation has been rescinded. Talk to a perinatologist for a definitive answer regarding PAI