I was prescribed biaxin (clarithromycin) for an ear infection, but it's causing insomnia. is it safe to take alka seltzer sinus night formula to clear my nose & sleep?

Mixing drugs: There should be no significant interactions between Biaxin (clarithromycin) and AlkaSelzer Sinus medications.

Yes: It's OK short term to take the medication you request with Biaxin (clarithromycin) - there are no interactions or contraindications. However, I doubt very much your insomnia is due to our taking Biaxin (clarithromycin). It is just not a side effect of that medication. It is possible you are having trouble sleeping because of the ear infection and nasal congestion.