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A member asked:
Any major risks with a combo of 300 mg of bupropion, 20 mg of escitalopram and adding 20 mg of omeprazole? risk of serotonin syndrome or seizure?
A doctor has provided 1 answer
Theory yes Serotonin: Omeprazole is a MILD blocker of liver metabolism (and 20 is low dose). Those are average doses of two antidepressants. They have a WIDE margin of safety. So, serotonin syndrome (two antidepressants both raising serotonin) or seizures (too much welbutin) is a conceivable concern. But it sure isn't likely. Unless there's something else to cause seizures or other serotonin drugs.
Answered 9/28/2016
4.1k views
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