Depends: How bad depends on where the clot is. In a superficial vein, it is just an annoyance. In the major artery of the brain, it would be very bad. Unresponsive means not responding to treatment. Go to this site for more info: http://www.mayoclinic.org/symptoms/blood-clots/basics/definition/SYM-20050850
Answered 6/10/2017
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