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A member asked:
How does the metabolism of isotretinoin damage the liver to the extent that increases in liver transaminase is a common consequence of its usage?
A doctor has provided 1 answer
Direct injury: Isotretinoin may cause direct injury to liver cells in 10-15 % of patient with elevation of liver enzyme the effect may be temporary and may go away but may persist in less than 1% users.
Answered 6/26/2014
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