A member asked:

I have painful neuropathy in my feet, lyrica (pregabalin) didn't help, gabapenten didn't work, would a small dose of both combined work?

5 doctors weighed in across 4 answers
Dr. Ruth Seaman answered

Specializes in Psychiatry

No: Lets find out why you have painful neuropathy first. Have you seen a neurologist and been tested? What is causing the neuropathy? Metro phoenix has top tier neurologists thanks to barrows (and mayo). Accurately identify cause first, then best treatment. (small fiber neuropathy; diabetes; plexopathy; b12; alcohol; etc). Gabapentin and Lyrica (pregabalin) act nearly identically. Dosing optimized?

Answered 12/7/2014

4.2k views

Thank
Dr. Paul Grin answered

Specializes in Pain Management

No mixing : Gabapentine and Pregabalin (lyrica) are almost the same medications. Lyrica (pregabalin) is commonly used for peripheral neuropathy. Rec.: see your doctor for medication adjustment and referral to east-west integrative medicine (e.G acupuncture).

Answered 12/7/2014

4.2k views

Thank
Dr. Narmo Ortiz answered

Specializes in Podiatry

Neuropathy in feet: I would not recommend to mix both medications without consulting with the physician(s) that prescribed them in the first place. You also did not mention what is the main known cause for your foot neuropathy.

Answered 9/21/2014

4.2k views

Thank

Avoid taking both: Both Lyrica (pregabalin) and Gabapentin have the same mechanism of action and work on the same receptors in your body. Therefore, it is not recommended to take both. If you are not at max dose, your doctor may suggest increase the dose of either of these medications to help control the pain. Another consideration would be to try a different class of medications for neuropathic pain.

Answered 12/7/2014

4.2k views

Thank

Related Questions