A member asked:

I have pretty severe raynaud's. i also had a + ana twice and have low c3 & c4 levels, but no other symptoms. dr is unsure of what's going on. ideas?

A doctor has provided 1 answer

Worth watching: Labs in rheumatologic disease are a paradox. There are a lot of them with varying sensitivities and specificities, but the diagnosis is made on history and physical. Low C3 / C4 would mean less than how you feel overall -- if raynaud's is your only real problem and you feel well, i'd urge you to ignore even a high-titer ana. You already know that many folks your age have a low-titer positive ana.

Answered 2/13/2015

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