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A member asked:
Have borderline low c3 and c4 complement levels and low 1:80 titre positive ana speckled. with symptoms relating to sle and sjorgrens - atypical ?
A doctor has provided 1 answer
Atypical for what?: Rheumatic disease generally requires a cluster of suggestive symptoms which is supported by lab studies. I do not know your symptoms, but your labs are not particularly suggestive of anything.
Answered 1/1/2013
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Sle dx. C3 is always low for years. C4 has never been low. I realize sle diagnosis is more complicated but aren't both complements usually low in sle?
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