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A 28-year-old female asked:

Is it normal to have low c3&c4 serum? i had a positive ana over five years ago also. now just have low c3&4. should i be worried? i have felt sick. ty

1 doctor answer1 doctor weighed in
Dr. John Chiu
Allergy and Immunology 59 years experience
You'd be: If you feel sick for a long time, you'd be worried. A low C3 & C4 especially in the presence of high ANA titer may point to an active autoimmune process. See a rheumatologist.
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Last updated Apr 27, 2015


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