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A 28-year-old female asked:

Is it normal to have low c3&c4 serum? i had a positive ana over five years ago also. now just have low c3&4. should i be worried? i have felt sick. ty

1 doctor answer • 1 doctor weighed in
Dr. John Chiu
Dr. John Chiuanswered
Allergy and Immunology 59 years experience
You'd be: If you feel sick for a long time, you'd be worried. A low C3 & C4 especially in the presence of high ANA titer may point to an active autoimmune process. See a rheumatologist.
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Diagnosed w/lupus 10 years ago &have been on plaqunenil. For past 6 years, my SED rate, c3, c4, and crp have been normal.my double stranded dna has been always negative. I have Ana 1:640 and other qualifying symptoms. Do I no longer have lupus ?
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Last updated Apr 27, 2015

Found in:

Serum›ANA

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