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A 47-year-old female asked:

I just had a test for c4, c 3, and ch50, i also have a high speckled ana and have had a low c3. can you tell me what the doctor is looking for?

1 doctor answer1 doctor weighed in
Dr. Ed Friedlander
Pathology 44 years experience
Lupus etc: As a lab doctor, I am forever remind people that the history and physical mean far more than the numbers. If the ANA is high-titer, and the pattern is speckled, it suggests any of a host of "connective tissue diseases"; ch50 and the others monitor the activity of lupus. Since no one knows what lupus really is, the labs are only a small part of the picture and the decision to rx may be a joint one.

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Last updated Jun 10, 2014

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