Is ast of 37 and alt of 49 in blood something to be concerned about? they are listed as high according to lab and i've been exhibiting fatigue.

Needs follow-up: Abnormal liver function tests can be a common finding, but still require follow-up and further evaluation to be safe. Things like fatty infiltration (hepatic steatosis) can be causative, and weight loss will cure that in time, and other causes can be viral hepatitis, gall bladder disease, other liver issues, medications you may be taking, alcohol use, etc. Get followed up by your dr. For eval.

Fatty liver or else?: There are 2 kinds of liver enzyme abnormalities--that signal disease of the liver cells or of the bile ducts. Abnormal liver tests may reflect fatty liver, too much alcohol, toxic exposure, occupational exposures, lot's of viral infections, metabolic problems, familial liver diseases, as well as problems with gallbladder, bile ducts, and pancreas. Need more tests to narrow the possiblities.

Yes: You'll get a workup, probably starting with a repeat after two weeks off alcohol and all unneeded meds. If they're still up, you'll get screened for a couple of treatable medical illnesses. This would be a great time, while you're waiting, to get back into a fitness-focused lifestyle. Best wishes.