A member asked:

After i started taking plaquenil (hydroxychloroquine) for sle in september my anti-tpo has normalized. however, it hasn't had any effect on my ana and anti-ssa. how come?

2 doctors weighed in across 2 answers
Dr. Stevan Cordas answered

Specializes in Internal Medicine

On Plaquinil: If it permits a chemical remission it may take a while. Not all antibodies follow the same rules. Watch clinical symptoms and inflammatory markers.

Answered 2/21/2014

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The: ANA levels may differ occasionally from day to day, or lab to lab. Medications of sjogrens or lupus typically will not affect the titer itself. That also applies for your ssa antibody.

Answered 6/10/2014

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