A member asked:

Is beta thalassemia major andd hb e/beta thalassemia same?

2 doctors weighed in across 2 answers
Dr. Maulik Shah answered

Specializes in Clinical Genetics

No: Beta thalassemia is a disorder of hemoglobin. Numerous different mutations can result in altered hemoglobin. In beta thal major, there are two abnormal "beta" genes. In hg e disease due to a specific mutation in the beta chain. In hbe/beta thal, one of the altered genes is hbe and the other is in hbb. Hbe/beta thall can be very variable.

Answered 2/12/2014

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Not the same.: Hemoglobin e is found in the asian population frequently and may be seen with thal trait. Thal major is a serious problem requiring much intervention, including transfusions and frequently splenectomy. Your doctor should be your guiding you. Pregnancy needs to be discussed with your doctor.

Answered 12/16/2018

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My baby have hb e/beta thalassemia? Is it sickle cell disease?

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