Beta- Thalassemia: 2 types of beta- thalassemia . Minor and major. Minor causes mild anemia and do not responds to iron therapy. Major, ( cooley anemia ) causes severe anemia, and pt requires multiple blood tranfusions. Major is the most common worldwide cause of transfusion- dependent anemia. Liver and spleen are markedly enlarged .Inadequate tranfusion leads to recurrent inf, fracture of bones, poor growth etc.
Answered 2/3/2014
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