A member asked:

Im currently on zoloft (sertraline) 50mg. if i don't see any changes and my doctor bumps up the medication, am i basically starting over with time?

4 doctors weighed in across 2 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Gradual titration: Your doctor should be gradually increasing your dose to a point where you have symptom relief, yet are not bothered with side effects. It is not a "starting over with time" situation. People may respond best to doses in the range of 100mg-150mg. Some people need more. You should be meeting regularly with your doctor to assess effectiveness, and/or make changes. Psychotherapy is needed also.

Answered 4/23/2016

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Dr. Aron Tendler answered

Specializes in Psychiatry

Not Exactly: I think what you are really asking is if you need to wait the full four weeks to see a benefit once the dosage is increased. Generally you want to wait the full for weeks for 100mg of zoloft (sertraline) to make sure it is or is not working but it may start to work even after 2 weeks. For depression the dosage is not increased above 100 unless there is some benefit noticed at that dose.

Answered 12/16/2016

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