A member asked:

What vaccines wear off and need boosters?

4 doctors weighed in across 3 answers

Tetanus vaccine: Currently, for the general population, tetanus and diphtheria immunity wear off as one gets older. This is the reason why booster shots are recommended every 10 years provided one does not encounter deep dirty contaminated wounds in which case a booster shot maybe administered if the last vaccine was given more than the last 5 years.

Answered 4/29/2012

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Tetanus.: The tetanus vaccine is known to be effective for 10 years. People are often not informed of this - but it should be redone every ten years.

Answered 7/7/2012

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Bacterial vaccines: Any vaccine i know of for a bacterial agent is likely to have a waning effect after several years. Tetanus toxoid is one example, but whooping cough (pertussis), pneumococcus (meningitis, pneumonia), meningococcus, diphtheria, cholera, all have their limitations.A few viral vaccines are boosted in infants whose immune system may not recognize & respond after one dose.

Answered 7/20/2012

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