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A member asked:
Dx sle. my c3 is almost always low but my c4 is always normal. have read sle has both low. alternative pathway? normal for lupus or misdiagnosis?
A doctor has provided 1 answer
Not unusual: C3 and C4 by themselves have limited value so i would not worry about your levels. If you have new onset renal insufficiency, protein in the urine and an active urine sediment then you have an issue. A low C3 by itself is not an issue.
Answered 2/13/2015
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