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A member asked:
I have a lupus overlap. my c3/c4 have always been low, but this month c4 is at its lowest while c3 is a low normal. why would it increase? esr is up.
2 doctors weighed in across 2 answers
Reactivation: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, drop in C4 and rise in ESR suggest reactivation of disease and you should consult your doctor.
Answered 10/31/2016
911 views
Disease activity: is causing increased consumption of your complement proteins, C3/C4 with the elevated ESR. See your rheumatologist /primary doctor for follow up and adhere to treatment plan, you will be fine, clinical response is more important than lab results in many instances, good luck
Answered 10/31/2016
909 views
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