A member asked:

Is it safe a chronic use of ppi as prophylactic for nsaids induced ulcer for patients taking nsaids for rheumatoid arthritis and osteoarthritis pain ?

2 doctors weighed in across 2 answers
Dr. Paul Grin answered

Specializes in Pain Management

Great idea: Recent study: "proton pump inhibitors decrease the risk of bleeding ulcers in high-risk NSAID or Aspirin users with very recent ulcer bleeding by approximately 75–85%., recent head-to-head randomized comparison of two preventive strategies (proton pump inhibitor plus non-selective NSAID vs. Cox-2-specific inhibitor)". Hope it helps.

Answered 6/24/2014

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Probably: Agree that it is useful to decrease GI bleeding and distress risk but it does in some studies seem to increase the risk of fractures it seems that this is due to less magnesium absorption so increasing magnesium supplementation might be a good idea this is what i personally do.

Answered 6/10/2014

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