Yes, but not alone: The large intestine has been transplanted many times in the past, but only as part of a small intestine transplant. The large intestine has two jobs: hold stool and absorb fluid. For this reason, it is beneficial in intestine transplant patients to avoid diarrhea and dehydration. However, the risks of immune suppression medication don't warrant large intestine transplant by itself.
Answered 12/10/2017
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