A member asked:

My therapist&psychiatrist i saw when put on a 5150 want me2go back on antidepressants. im a meth addict&if i slip&use while on meds is that dangerous?

4 doctors weighed in across 2 answers

It could be: Cytochrome p450 enzyme systems are extensively involved in the metabolism of methadone, including especially 2d6 and 3a4 but also others. Your doctor can test these that are involved also in antidepressant metabolism plus more if he deems necessary. Charts are available at these websites: www.practicalpainmanagement.com/treatments/... www.ncbi.nlm.nih.gov/pmc/articles/pmc1852041 best wishes.

Answered 4/9/2016

4.6k views

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Dr. Blaine Messing answered

Specializes in Addiction Medicine

Essentially no.: The intermittent use of methamphetamine will not pose risk to you while taking antidepressants. It will however compromise the effectiveness of those medications in treating your depressive symptoms.

Answered 1/13/2014

4.6k views

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