A member asked:

Cbc: 11/15/13 - all normal with platelets at 377. cbc at 12/17/13 - all normal exc. platelets at 428. worried about sudden increase? is 428 serious enough to be a sign of cancer or other disease?

3 doctors weighed in across 2 answers

It is not serious: Your platelet count is slightly high. This doe snot necessarily mean anything serious. We do not worry about platelet counts unless they go above 450, 000. So i would sit on it for now and recheck one more time in 2-3 months time. If it is increasing, go see an internist for advice.

Answered 1/8/2014

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Discuss fully: Platelets are also acute reactants to inflammation or disease. Even simple infections or inflammatory conditions can cause platelet count to go up. The level is not alarming but if concerned observe, repeat and discuss the result with your doctor with some questions to be clarified.

Answered 12/30/2014

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