Why am i down in the dumps so bad? i take cymbalta (duloxetine) and lexapro with no improvement. i enjoy nothing any more

Talk with your doc: There are many reasons possible. Your chronic pain conditions and the oxycodone may be depressing in themselves. Your medication might not be at a sufficient dose to help, or you may need different meds or strategies. Talking with your doctor and/or a referral to a psychiatrist with expertise in psychopharmacology and treatment resistant depression mae helpful. Lots of treatments available!

Talk to a counselor: Or psychologist. Depression remedies include exercising, engaging in social interaction ; engrossing activities, practicing gratitude, doing kind things for others, learning ; practicing stress management, developing ; committing to meaningful goals, avoiding negative thinking ; negative comparisons with others, ; talking to empathic ; trusted people. Don't suffer any longer. Call right away.

Agree w Dr. Haupt: Besides having medications optimized by a psychiatrist - are you involved with non-medication forms of treatment? Talk about feelings ; address problems. Don't avoid them. Aim for 7.5 - 8 hours of sleep/ night. Daily physical activity is optimal in a green space. Eat healthfully. Cut out junk carbs, caffeine ; alcohol (or moderate). Try qi gong, tai chi, acupuncture, acupressure, homeopathy, .