A member asked:

Is having nsaid induced hives the same thing as being allergic to them? what if u have mild hives even when not taking nsaids, just worse w/them?

2 doctors weighed in across 2 answers
Dr. Kaleyathodi Bhat answered

Specializes in Allergy and Immunology

NSAID hives: Nsaid hives can be due to ige mediated immediate allergy, or more commonly prostaglandin mediated angioedema and urticaria. The fact that hives were before starting nsaid, it does not seem like it is an allergy to nsaid.

Answered 12/9/2013

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No: . Nsaid hypersensitivity is not an immune type of allergy. It seems based on blocking of the cycloxygenase -1 enzyme pathway, which increases active products of lipoxygenase pathway.The reponse varies from worsening other causes of hives to being the cause of hives. People with skin reactions often tolerate different nsaids.In NSAID respiratory disease all nsaids cause problems.

Answered 6/10/2014

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