Can you tell me some primary considerations when setting a weight loss goal?

There are MANY: What age were you when you were at a weight you were happy with? If you have to go back 10-15 years that may be a weight that is too low. What is your current age? Hormones need to be at certain levels ; be checked because they deplete with age. Like the sex hormones testosterone, estradiol, and progesterone. A fasting Insulin level is critical to know. These will determine what you can lose.