A member asked:

Can silent celiac be present if iga and igg are <2 (negative)? and causing neuropathy, w/high b12.

A doctor has provided 1 answer
Dr. Michael P Vaughn answered

Specializes in Allergy and Immunology

Celiac disease: The only reliable diagnosis for celiac disease is based on intestinal biopsies showing inflammatory damage that resolves when on a gluten-free diet. Blood testing for anti-dpg ot ttg are suggestive if positive but not definitive (negative testing does not eliminate celiac). Genetic testing is useful since the absence of hla-dq 2 or 8 alleles makes celiac disease unlikely (.

Answered 11/14/2018

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