Question 1

please describe the medication: sinemet (carbidopa and levodopa)?

Accepted Answer

L-DOPA: Sinemet (carbidopa and levodopa) is a brand combination of l-dopa, the precursor of dopamine, and carbidopa, used to prolong the plasma level for extended efficacy.  It is indicated to treat parkinson's disease, but has also some success in lewy body dementias, and even in other tremors. Of value in parkinson's for about 5-7 yrs, but may lose benefit beyond that point.  Used second-line to delay dyskinesia complications.

Question 2

milligrams for 6 hour sinemet (carbidopa and levodopa)? what is the dosage for this medication?

Accepted Answer

Dosages : Dosages are adjusted for the specific needs of each patient - there is no standard dose for any specific time period.  Sinemet (carbidopa and levodopa) comes in carbadopa-levodopa doses of 10-100, 25-250, and 25-100.  These can be combined and given at various times throughout the day to best relieve the symptoms of parkinson's disease.  If you are not sure of your dose or the dose of someone you are caring for, you need to call the doctor that prescribed the medication to clarify.  Good luck!

Question 3

is prozac (fluoxetine) safe to take with parkinson's medication such sinemet?

Accepted Answer

Usually, yes: Generally you can take Prozac (fluoxetine) with sinemet.  You need ongoing follow-up though, since either can cause changes in behavior and mental status.

Question 4

is it safe to take fluoxetine with parkinson's medications such as sinemet and requip (ropinirole)?

Accepted Answer

Mild interaction: There is no severe interaction although if the fluoxetine were to be sedating to you then you may feel somewhat sedated.  Additionally, the selective serotonin reuptake inhibitors that include fluoxetine have been known to produce mild extrapyramidal effects through obscure mechanisms.  This would translate into a potential for mild motoric phenomena that would be only a nuisance. Stay safe!

Question 5

what is the difference between parkinson's drug sinemet and stalevo (carbidopa and levodopa and entacapone)?

Accepted Answer

COMT inhibitor: Entacaptone is a selective catecholamine-o methyl transferase (comt) inhibitor that increases the bioavailabilty of dopamine. Like Carbidopa in sinemet it does not cross the blood brain barrier. Stalevo (carbidopa and levodopa and entacapone) is a combination of l dopa, Carbidopa and entacaptone. Sinemet is a combination of Carbidopa and l-dopa.

Question 6

my mom, safia, 60 years old, resident of pakistan has drug induced parkinsonism, which is bothering a lot & worsening. sinemet (carbidopa and levodopa) 25/250 every 4.5 hours?

Accepted Answer

Tachyphylaxis.: Dosing of Sinemet (carbidopa and levodopa) is a little strange, requiring front loading in the day and a long gap at night without dosing.  If taken like most other medications, on a more regular dosing interval, tachyphylaxis develops, which essentially means the efficacy of the medication reduces.

Question 7

is it safe to take clonazepam for sleep with sinemet (carbidopa and levodopa) for parkinsons patient? are there any drug interactions?

Accepted Answer

Probably safe...: ...but not especially the best choice! Although medications in that class (benzodiazepines) allay anxiety and can relax muscle spasm, they also interfere with normal sleep architecture and increase the risk of falling. I would certainly advise that you discuss this with your neurologist or a psychiatrist trained in sleep disorders or with additional training in geropsychiatry.

Question 8

can a parkinson patient who takes sinemet&requip take sudafed for congestion & robotussin to losen mucus together? it says not to take with maoi drugs

Accepted Answer

Yes: Neither sinemet or Requip (ropinirole) are MAO inhibitors. Sudafed can affect blood pressure.

Question 9

what is the typical dosage of sinemet (carbidopa and levodopa) cr?

Accepted Answer

Sinemet-CR: This has to be determined by careful titration thru your doctor. Initial dose is usually 50-200. Consult your Neurologist.

Question 10

what does sinemet (carbidopa and levodopa) consist of and what is cr?

Accepted Answer

See below: Sinemet® (carbidopa-levodopa) is a combination of Carbidopa and Levodopa for the treatment of parkinson's disease and syndrome.Sinemet® cr (carbidopa-levodopa) is a sustained-release combination of Carbidopa and Levodopa for the treatment of parkinson's disease and syndrome.

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Doctor answers about:

Sinemet cr medication

A member asked:

Please describe the medication: sinemet (carbidopa and levodopa)?

A member asked:

Milligrams for 6 hour sinemet (carbidopa and levodopa)? what is the dosage for this medication?

A member asked:

Is prozac (fluoxetine) safe to take with parkinson's medication such sinemet?

A member asked:

Is it safe to take fluoxetine with parkinson's medications such as sinemet and requip (ropinirole)?

A member asked:

What is the difference between parkinson's drug sinemet and stalevo (carbidopa and levodopa and entacapone)?

A member asked:

My mom, safia, 60 years old, resident of pakistan has drug induced parkinsonism, which is bothering a lot & worsening. sinemet (carbidopa and levodopa) 25/250 every 4.5 hours?

A member asked:

Is it safe to take clonazepam for sleep with sinemet (carbidopa and levodopa) for parkinsons patient? are there any drug interactions?

A member asked:

Can a parkinson patient who takes sinemet&requip take sudafed for congestion & robotussin to losen mucus together? it says not to take with maoi drugs

A member asked:

What is the typical dosage of sinemet (carbidopa and levodopa) cr?

A member asked:

What does sinemet (carbidopa and levodopa) consist of and what is cr?

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