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A member asked:

My mom, safia, 60 years old, resident of pakistan has drug induced parkinsonism, which is bothering a lot & worsening. sinemet (carbidopa and levodopa) 25/250 every 4.5 hours?

A doctor has provided 1 answer

Tachyphylaxis.: Dosing of Sinemet (carbidopa and levodopa) is a little strange, requiring front loading in the day and a long gap at night without dosing. If taken like most other medications, on a more regular dosing interval, tachyphylaxis develops, which essentially means the efficacy of the medication reduces.

Dr Chuu agreed

Answered 11/28/2017

3.3k views

Thank

Related Questions

A member asked:

What is the protocol for switching a Parkinsons patient from regular Sinemet (carbidopa and levodopa) to Sinemet (carbidopa and levodopa) CR?

A doctor has provided 1 answer

A member asked:

Is Stalevo (carbidopa and levodopa and entacapone) superior to Sinemet for Parkinsons? Is one better than the other?

A doctor has provided 1 answer

A member asked:

High sinemet (carbidopa and levodopa) doses without Parkinson's how do I get off sinemet (carbidopa and levodopa). No doctor at present.?

4 doctors weighed in across 2 answers

A member asked:

I started symptoms of parkinsons.Loss of smell almost total now.Ridgity and loss of balence has gotten worse.Would isradipine help.Sinemet (carbidopa and levodopa) helped .?

3 doctors weighed in across 2 answers

A member asked:

Rephrasing my question. My Stalevo (carbidopa and levodopa and entacapone) controls my Parkinson's but some times when I take it, I get stiff and have trouble moving. What is causing this ?

A doctor has provided 1 answer

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