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A member asked:
My mom, safia, 60 years old, resident of pakistan has drug induced parkinsonism, which is bothering a lot & worsening. sinemet (carbidopa and levodopa) 25/250 every 4.5 hours?
A doctor has provided 1 answer
Tachyphylaxis.: Dosing of Sinemet (carbidopa and levodopa) is a little strange, requiring front loading in the day and a long gap at night without dosing. If taken like most other medications, on a more regular dosing interval, tachyphylaxis develops, which essentially means the efficacy of the medication reduces.
Answered 11/28/2017
3.3k views
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What is the protocol for switching a Parkinsons patient from regular Sinemet (carbidopa and levodopa) to Sinemet (carbidopa and levodopa) CR?
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Is Stalevo (carbidopa and levodopa and entacapone) superior to Sinemet for Parkinsons? Is one better than the other?
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High sinemet (carbidopa and levodopa) doses without Parkinson's how do I get off sinemet (carbidopa and levodopa). No doctor at present.?
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