Q: lupus anticoagulant eval. the ref range is <45sec. does the result matter if its over 45? for example, is a result of 51 more indicative of an issue than 46? if the la screen and drvvt screen is high and confirm is - what factors should be checked?

: Pleas touch base with the doctor who ordered the test. Background &amp; context is needed.

Q: my pcp ordered a lupus screen. lupus anticoagulant screen was 31. drvvt was 47(standard range under 45). drvvt 1:1 negative. what does this mean? is it concerning that my drvvt was high? i will talk to my dr. i have 4 other autoimmune dis?

: This is a test for the presence of the lupus anticoagulant. Since your DRVVT ratio was normal, I doubt that the borderline reading of 47 is significant. When it's elevated the lab usually reflexively tests other coagulation tests for more information. The rheumatologist can advise you best as he/she knows your clinical history &amp; findings.

Q: when testing for antiphospolipid antibody syndrome, does taking baby aspirin affect the lupus anticoagulant (ptt-la, drvvt) test results?

It should not: The aspirin inhibits platelets not other parts of the clotting cascade.

Q: have rheumatoid factor 15, cardiolipin igm 31, smith anti of 12, dsdna 11, rnp 24, drvvt 0.85, sed rate 8mm...and bilateral avn femoral heads.... lupus?

Need to examine: There are multiple criteria that need to be met to make a diagnosis of lupus. You need to consult a rheumatologist. Visit this site for Lupus diagnostic criteria: https://www.rheumtutor.com/diseases/systemic-lupus-erythematosus/

Q: my dsdna double strand reference was 3.45 and very symptomatic.. s this a positive for lupus how is it scored?

Possibly: this is one of the many blood tests used to diagnose lupus..you should consult your rheumatologist to have them run a full battery of tests

Q: can i have lupus if my ana is positive, tired is 1:320 homogeneous diffuse, but ena panel is negative. i do have some s/s?

See a rheumatologist: For assessment, lupus isn't an easy diagnosis to make, an expert would better help you, good luck

Q: will my ana test positive if my lupus is mild?

Yes: The degree of ANA positivity does not correlate with disease activity.

Question 1

lupus anticoagulant screen w/ ref. is it normal for the results to change in a few months? prolonged screen in october. now prolonged screen and drvvt 1:1 confirmation positive. the mix was corrected. what factors could be deficient-v? x? thanks?

Accepted Answer

: Factor X deficiency.

Question 2

lupus anticoagulant screen w/ reflex. is it normal for the results to change/worsen in 5 months? first time in october the drvvt confirmation was negative. 5 months later it was positive. both times had a high drvvt screen. why would results change?

Accepted Answer

: Tests for LA need to be confirmed after 3 months because medication(s) or some clinical events, e.g. infection, can affect the result.

Question 3

had lupus anticoagulant eval w/reflex done twice in 3 months. 1st drvvt screen high. 2nd screen high, confirmation positive, mix corrected. what factor deficiency can cause these results? how would you interpret these results-weak la or factor def?

Accepted Answer

: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, there is not sufficient information in your message to provide a meaningful response.    Wish you good health!

Question 4

lupus anticoagulant eval. the ref range is <45sec. does the result matter if its over 45? for example, is a result of 51 more indicative of an issue than 46? if the la screen and drvvt screen is high and confirm is - what factors should be checked?

Accepted Answer

: Pleas touch base with the doctor who ordered the test. Background &amp; context is needed.

Question 5

my pcp ordered a lupus screen. lupus anticoagulant screen was 31. drvvt was 47(standard range under 45). drvvt 1:1 negative. what does this mean? is it concerning that my drvvt was high? i will talk to my dr. i have 4 other autoimmune dis?

Accepted Answer

: This is a test for the presence of the lupus anticoagulant. Since your DRVVT ratio was normal,  I doubt that the borderline reading of 47 is significant. When it's elevated the lab usually reflexively tests other coagulation tests for more information.  The rheumatologist can advise you best as he/she knows your clinical history &amp; findings.

Question 6

when testing for antiphospolipid antibody syndrome,  does taking baby aspirin affect the lupus anticoagulant (ptt-la, drvvt) test results?

Accepted Answer

It should not: The aspirin inhibits platelets not other parts of the clotting cascade.

Question 7

have rheumatoid factor 15, cardiolipin igm 31, smith anti of 12, dsdna 11, rnp 24, drvvt 0.85, sed rate 8mm...and bilateral avn femoral heads.... lupus?

Accepted Answer

Need to examine: There are multiple criteria that need to be met to make a diagnosis of lupus. You need to consult a rheumatologist. 
Visit this site for Lupus diagnostic criteria:
https://www.rheumtutor.com/diseases/systemic-lupus-erythematosus/

Question 8

my dsdna double strand reference was 3.45 and very symptomatic.. s this a positive for lupus how is it scored?

Accepted Answer

Possibly: this is one of the many blood tests used to diagnose lupus..you should consult your rheumatologist to have them run a full battery of tests

Question 9

can i have lupus if my ana is positive, tired is 1:320 homogeneous diffuse, but ena panel is negative. i do have some s/s?

Accepted Answer

See a rheumatologist: For assessment, lupus isn't an easy diagnosis to make, an expert would better help you, good luck

Question 10

will my ana test positive if my lupus is mild?

Accepted Answer

Yes: The degree of ANA positivity does not correlate with disease activity.

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Doctor answers about:

Positive drvvt without lupus

A member asked:

Lupus anticoagulant screen w/ ref. is it normal for the results to change in a few months? prolonged screen in october. now prolonged screen and drvvt 1:1 confirmation positive. the mix was corrected. what factors could be deficient-v? x? thanks?

A member asked:

Lupus anticoagulant screen w/ reflex. is it normal for the results to change/worsen in 5 months? first time in october the drvvt confirmation was negative. 5 months later it was positive. both times had a high drvvt screen. why would results change?

A member asked:

Had lupus anticoagulant eval w/reflex done twice in 3 months. 1st drvvt screen high. 2nd screen high, confirmation positive, mix corrected. what factor deficiency can cause these results? how would you interpret these results-weak la or factor def?

A member asked:

Lupus anticoagulant eval. the ref range is <45sec. does the result matter if its over 45? for example, is a result of 51 more indicative of an issue than 46? if the la screen and drvvt screen is high and confirm is - what factors should be checked?

A member asked:

My pcp ordered a lupus screen. lupus anticoagulant screen was 31. drvvt was 47(standard range under 45). drvvt 1:1 negative. what does this mean? is it concerning that my drvvt was high? i will talk to my dr. i have 4 other autoimmune dis?

A member asked:

When testing for antiphospolipid antibody syndrome, does taking baby aspirin affect the lupus anticoagulant (ptt-la, drvvt) test results?

A member asked:

Have rheumatoid factor 15, cardiolipin igm 31, smith anti of 12, dsdna 11, rnp 24, drvvt 0.85, sed rate 8mm...and bilateral avn femoral heads.... lupus?

A member asked:

My dsdna double strand reference was 3.45 and very symptomatic.. s this a positive for lupus how is it scored?

A member asked:

Can i have lupus if my ana is positive, tired is 1:320 homogeneous diffuse, but ena panel is negative. i do have some s/s?

A member asked:

Will my ana test positive if my lupus is mild?

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