Question 1

what's your opinion on taking a long acting benzodiazepine bid, in combination with a very short acting one (xanax, ativan) prn? i've been on xanax 2m

Accepted Answer

Not a good idea: The benzodiazepines such as Xanax or Ativan  are addicting. I suggest you speak with your prescriber about alternatives such as behavioral therapy, alternative anxiety meds and serotonergic meds.

Question 2

which benzodiazepine drug is be most effective as a sleeping tablet, chlordiazepoxide or diazepam?

Accepted Answer

Neither is/are safe: Chlordiazepoxide (librium) has a half-life of 5-30hrs w/active metabolites staying in your system 3-200hrs! diazepam (valium) has a half-life of 30-60hrs w/active metabolites staying in your system 30-100hrs. Neither are indicated (approved) for use in insomnia. All benzo & other non-benzo sedative-hypnotics are associated w/increase risk of injuries & even mortality. http://bit.ly/kbqlwd.

Question 3

hello, i take valium 5mg, 3x a day as prescribed. i am searching for possibly a new benzodiazipine, whats your opinion on an equal dosing of librium?

Accepted Answer

10x3: You would take 10mg of librium 3x per day.
I would advise of course to check with your doctor first and make sure to understand that long term use of benzo's are generally not recommended except for very rare situations due to side effects.

Question 4

why are benzodiazepines no longer listed as schedule iv drugs?

Accepted Answer

Addiction: Benzos are schedule II drugs because of their high rate of becoming habit forming and addictive.

Question 5

i'm currently prescribed librium for g.a.d. and s.a.d., but i'd like to ask my doctor for a replacement that acts faster and longer. would xanax (alprazolam) work?

Accepted Answer

Talk to your doctor : Xanax (alprazolam) is quicker acting but short-lived. It has a high addiction risk. An SSRI is preferred for long term use. Klonopin could be added for short term use till the SSRI starts to work.

Question 6

in the event of excitotoxicity occurring after withdrawing from a benzodiazepine, would excitotoxicity occur before or after a seizure occurs, i.e. would a seizure indicate that the glutamate concentration had reached excitotoxic levels?

Accepted Answer

Yes: Since the seizure would be caused by the excitotoxity phenomenon, it would need to occur before the seizure. So the level of glutamate was most likely at high toxic levels.

Question 7

can you tell me what is the best benzodiazepine?

Accepted Answer

There is no "best": Benzodiazepines all work on the same receptors, and pretty much do the same thing.  Some are short-acting, others intermediate, others long-acting. Some are rapidly absorbed, others slowly.  Some hit the brain very fast, others much more slowly.  If you want something for temporary anxiety, a rapidly-absorbed short acting drug (like xanax (alprazolam) or ativan) may be best, for gad, Clonazepam or librium.

Question 8

how many librium would it take to really overdose?

Accepted Answer

Cant say: Depends on how much sedatives you are currently using.

Question 9

can certain benzodiazepines treat pain?

Accepted Answer

Not directly: They can cut anxiety & relax muscles which may help indirectly.

Question 10

can librium and lorazepam be taken together?

Accepted Answer

Not a good idea: I'm not sure why you would. Both are in the same classification of meds, namely benzodiazepines. Both are central nerve system depressants and similarly in the brain. The risk of overdosing or causing respiratory depression is high.

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Doctor answers about:

Librium long acting benzodiazepine

A member asked:

What's your opinion on taking a long acting benzodiazepine bid, in combination with a very short acting one (xanax, ativan) prn? i've been on xanax 2m

A member asked:

Which benzodiazepine drug is be most effective as a sleeping tablet, chlordiazepoxide or diazepam?

A member asked:

Hello, i take valium 5mg, 3x a day as prescribed. i am searching for possibly a new benzodiazipine, whats your opinion on an equal dosing of librium?

A member asked:

Why are benzodiazepines no longer listed as schedule iv drugs?

A member asked:

I'm currently prescribed librium for g.a.d. and s.a.d., but i'd like to ask my doctor for a replacement that acts faster and longer. would xanax (alprazolam) work?

A member asked:

In the event of excitotoxicity occurring after withdrawing from a benzodiazepine, would excitotoxicity occur before or after a seizure occurs, i.e. would a seizure indicate that the glutamate concentration had reached excitotoxic levels?

A member asked:

Can you tell me what is the best benzodiazepine?

A member asked:

How many librium would it take to really overdose?

A member asked:

Can certain benzodiazepines treat pain?

A member asked:

Can librium and lorazepam be taken together?

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